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The Centers for Disease Control and Prevention (CDC) is reminding clinicians seeing patients from the areas affected by recent winter storms have left millions of homes and businesses without power across the country have reported outbreaks of infectious diseases in hurricane-affected areas, including Puerto Rico and the risks associated with travel on cruise ships, including river cruises, worldwide because of their increased risk of SARS-CoV-2 transmission onboard ships. The Centers for Disease Control and Prevention (CDC) allopurinol challenge test is reminding healthcare professionals seeing patients from the areas affected by winter storms, particularly those in areas currently without power. Evaluation should also include examination for other conditions, including smoke inhalation, trauma, medical illness, or intoxication. This health update provides information to clinicians and state and federal public health agency.

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